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Synosteo is a unique combination containing calcium citrate, calcium lactate, vitamin D3 and vitamin K2 in strengths according to the international guidelines. It is the only product currently available in the Greek market that combines the benefits of calcium, vitamin D and vitamin K2 in a single daily intake.
Adequate calcium intake is a fundamental aspect of any osteoporosis prevention or treatment program and part of a lifestyle for healthy bones at any age.
Vitamin D plays a major role in calcium absorption and bone health and may be important in muscle performance, balance, and falling risk. Moreover, optimal vitamin D status may enhance the response to bisphosphonate therapy, increase BMD, and prevent fractures.
Vitamin K is a fat-soluble vitamin, important for the function of numerous proteins within the body. There are two naturally occurring forms: phylloquinone (vitamin K1) and menaquinone (vitamin K2). Adequate intake of vitamin K2 has been shown to lower the risk of vascular damage because it inhibits calcium from depositing in the vessel walls and to effectively improve markers of bone health.
Synosteo is a unique formulation and its administration combines several advantages:
It contains calcium citrate and calcium lactate
The two main forms of calcium in supplements are carbonate and citrate. Due to its dependence on stomach acid for absorption, calcium carbonate is absorbed most efficiently when taken with food, whereas calcium citrate is absorbed equally well when taken with or without food and is also useful for people with achlorhydria, inflammatory bowel disease, or absorption disorders. Calcium citrate supplements should also be recommended for individuals treated with H2 blockers or proton pump inhibitors.
Some individuals who take calcium supplements might experience gastrointestinal side effects including gas, bloating, constipation, or a combination of these symptoms. Calcium carbonate appears to cause more of these side effects than calcium citrate and this may have negative effects on patient’s compliance.
Because pH levels have little to no impact on calcium lactate absorbability, it can be taken with or without food and it also be given to individuals with intolerance to milk or lactose.
Citrate salts prevent new stone formation and reduce further stone growth in patients with residual stones that predominantly contain oxalate.
Combined calcium and vitamin D formulation
The primary function of vitamin D is the regulation of intestinal calcium and phosphorus absorption. Even in a sunny country like Greece, statistics show that vitamin D deficiency is not rare. Synosteo contains the recommended daily of dose calcium and vitamin D in a single sachet which can be taken any time of the day regardless of food consumption.
Pleasant orange flavor
Poor compliance reduces the efficacy of calcium supplementation. Synosteo possess a pleasant orange flavor and can be easily taken any time during the day.
It contains vitamin K2
Deficiency of vitamin K2 is associated with low BMD and increased risk for osteoporotic fracture and for calcification of the blood vessels.
Gluten and lactose free.
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